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1

Heritability in the genome-wide association era

Zaitlen, Noah, Kraft, Peter

Journal:

Year:

2012

Language:

english

File:

PDF, 365 KB

english, 2012

2

Dual gene activation and knockout screen reveals directional dependencies in genetic networks

Boettcher, Michael, Tian, Ruilin, Blau, James A, Markegard, Evan, Wagner, Ryan T, Wu, David, Mo, Xiulei, Biton, Anne, Zaitlen, Noah, Fu, Haian, McCormick, Frank, Kampmann, Martin, McManus, Michael T

Journal:

Nature Biotechnology

Year:

2018

Language:

english

File:

PDF, 10.13 MB

english, 2018

3

Genetic effects on the commensal microbiota in inflammatory bowel disease patients

Aschard, Hugues, Laville, Vincent, Tchetgen, Eric Tchetgen, Knights, Dan, Imhann, Floris, Seksik, Philippe, Zaitlen, Noah, Silverberg, Mark S., Cosnes, Jacques, Weersma, Rinse K., Xavier, Ramnik, Beau

Journal:

Year:

2019

Language:

english

File:

PDF, 5.27 MB

english, 2019

4

Imputation aware meta-analysis of genome-wide association studies

Noah Zaitlen, Eleazar Eskin

Journal:

Genetic Epidemiology

Year:

2010

Language:

english

File:

PDF, 280 KB

english, 2010

5

Using Extended Genealogy to Estimate Components of Heritability for 23 Quantitative and Dichotomous Traits

Zaitlen, Noah, Kraft, Peter, Patterson, Nick, Pasaniuc, Bogdan, Bhatia, Gaurav, Pollack, Samuela, Price, Alkes L., Visscher, Peter M.

Journal:

Year:

2013

Language:

english

File:

PDF, 284 KB

english, 2013

6

Advantages and pitfalls in the application of mixed-model association methods

Yang, Jian, Zaitlen, Noah A, Goddard, Michael E, Visscher, Peter M, Price, Alkes L

Journal:

Nature Genetics

Year:

2014

Language:

english

File:

PDF, 373 KB

english, 2014

7

Massively parallel functional annotation of 3′ untranslated regions

Zhao, Wenxue, Pollack, Joshua L, Blagev, Denitza P, Zaitlen, Noah, McManus, Michael T, Erle, David J

Journal:

Nature Biotechnology

Year:

2014

Language:

english

File:

PDF, 995 KB

english, 2014

8

Molecular Genetic Analysis Subdivided by Adversity Exposure Suggests Etiologic Heterogeneity in Major Depression

Peterson, Roseann E., Cai, Na, Dahl, Andy W., Bigdeli, Tim B., Edwards, Alexis C., Webb, Bradley T., Bacanu, Silviu-Alin, Zaitlen, Noah, Flint, Jonathan, Kendler, Kenneth S.

Journal:

American Journal of Psychiatry

Year:

2018

Language:

english

File:

PDF, 1.98 MB

english, 2018

9

Genetic effects on the commensal microbiota in inflammatory bowel disease patients

Aschard, Hugues, Laville, Vincent, Tchetgen, Eric Tchetgen, Knights, Dan, Imhann, Floris, Seksik, Philippe, Zaitlen, Noah, Silverberg, Mark S., Cosnes, Jacques, Weersma, Rinse K., Xavier, Ramnik, Beau

Journal:

Year:

2019

File:

PDF, 5.27 MB

2019

10

Ultrarare variants drive substantial cis heritability of human gene expression

Hernandez, Ryan D., Uricchio, Lawrence H., Hartman, Kevin, Ye, Chun, Dahl, Andrew, Zaitlen, Noah

Journal:

Nature Genetics

Year:

2019

Language:

english

File:

PDF, 7.65 MB

english, 2019

11

A Robust Method Uncovers Significant Context-Specific Heritability in Diverse Complex Traits

Dahl, Andy, Nguyen, Khiem, Cai, Na, Gandal, Michael J., Flint, Jonathan, Zaitlen, Noah

Journal:

The American Journal of Human Genetics

Year:

2020

File:

PDF, 1.70 MB

2020

12

Genotyping common and rare variation using overlapping pool sequencing

Dan He, Noah Zaitlen, Bogdan Pasaniuc, Eleazar Eskin, Eran Halperin

Journal:

BMC Bioinformatics

Year:

2011

Language:

english

File:

PDF, 272 KB

english, 2011

13

Combining effects from rare and common genetic variants in an exome-wide association study of sequence data

Hugues Aschard, Weiliang Qiu, Bogdan Pasaniuc, Noah Zaitlen, Michael H Cho, Vincent Carey

Journal:

BMC Proceedings

Year:

2011

Language:

english

File:

PDF, 207 KB

english, 2011

14

Genome-wide association analysis of metabolic traits in a birth cohort from a founder population

Sabatti, Chiara, Service, Susan K, Hartikainen, Anna-Liisa, Pouta, Anneli, Ripatti, Samuli, Brodsky, Jae, Jones, Chris G, Zaitlen, Noah A, Varilo, Teppo, Kaakinen, Marika

Journal:

Nature Genetics

Year:

2008

Language:

english

File:

PDF, 13.03 MB

english, 2008

15

Variance component model to account for sample structure in genome-wide association studies

Kang, Hyun Min, Sul, Jae Hoon, Service, Susan K, Zaitlen, Noah A, Kong, Sit-yee, Freimer, Nelson B, Sabatti, Chiara, Eskin, Eleazar

Journal:

Nature Genetics

Year:

2010

Language:

english

File:

PDF, 1.28 MB

english, 2010

16

New approaches to population stratification in genome-wide association studies

Price, Alkes L., Zaitlen, Noah A., Reich, David, Patterson, Nick

Journal:

Nature Reviews Genetics

Year:

2010

Language:

english

File:

PDF, 523 KB

english, 2010

17

Extremely low-coverage sequencing and imputation increases power for genome-wide association studies

Pasaniuc, Bogdan, Rohland, Nadin, McLaren, Paul J, Garimella, Kiran, Zaitlen, Noah, Li, Heng, Gupta, Namrata, Neale, Benjamin M, Daly, Mark J, Sklar, Pamela, Sullivan, Patrick F, Bergen, Sarah, Moran,

Journal:

Nature Genetics

Year:

2012

Language:

english

File:

PDF, 1.46 MB

english, 2012

18

Leveraging Genetic Variability across Populations for the Identification of Causal Variants

Noah Zaitlen, Bogdan Paşaniuc, Tom Gur, Elad Ziv, Eran Halperin

Journal:

The American Journal of Human Genetics

Year:

2010

Language:

english

File:

PDF, 904 KB

english, 2010

19

Genome-wide Comparison of African-Ancestry Populations from CARe and Other Cohorts Reveals Signals of Natural Selection

Gaurav Bhatia, Nick Patterson, Bogdan Pasaniuc, Noah Zaitlen, Giulio Genovese, Samuela Pollack, Swapan Mallick, Simon Myers, Arti Tandon, Chris Spencer, Cameron D. Palmer, Adebowale A. Adeyemo, Ermeg

Journal:

The American Journal of Human Genetics

Year:

2011

Language:

english

File:

PDF, 564 KB

english, 2011

20

Multi-marker tagging single nucleotide polymorphism selection using estimation of distribution algorithms

Roberto Santana, Alexander Mendiburu, Noah Zaitlen, Eleazar Eskin, Jose A. Lozano

Journal:

Artificial Intelligence in Medicine

Year:

2010

Language:

english

File:

PDF, 475 KB

english, 2010

21

Leveraging the HapMap Correlation Structure in Association Studies

Noah Zaitlen, Hyun Min Kang, Eleazar Eskin, Eran Halperin

Journal:

The American Journal of Human Genetics

Year:

2007

Language:

english

File:

PDF, 650 KB

english, 2007

22

Leveraging population admixture to characterize the heritability of complex traits

Zaitlen, Noah, Pasaniuc, Bogdan, Sankararaman, Sriram, Bhatia, Gaurav, Zhang, Jianqi, Gusev, Alexander, Young, Taylor, Tandon, Arti, Pollack, Samuela, Vilhjálmsson, Bjarni J, Assimes, Themistocles L,

Journal:

Nature Genetics

Year:

2014

Language:

english

File:

PDF, 875 KB

english, 2014

23

A Nonparametric Test to Detect Quantitative Trait Loci Where the Phenotypic Distribution Differs by Genotypes

Aschard, Hugues, Zaitlen, Noah, Tamimi, Rulla M., Lindström, Sara, Kraft, Peter

Journal:

Genetic Epidemiology

Year:

2013

Language:

english

File:

PDF, 866 KB

english, 2013

24

Accurate Estimation of Expression Levels of Homologous Genes in RNA-seq Experiments

Paşaniuc, Bogdan, Zaitlen, Noah, Halperin, Eran

Journal:

Journal of Computational Biology

Year:

2011

Language:

english

File:

PDF, 923 KB

english, 2011

25

Genetic and environmental components of family history in type 2 diabetes

Cornelis, Marilyn C., Zaitlen, Noah, Hu, Frank B., Kraft, Peter, Price, Alkes L.

Journal:

Year:

2015

Language:

english

File:

PDF, 469 KB

english, 2015

26

Shift-Invariant Adaptive Double Threading: Learning MHC II–Peptide Binding

Zaitlen, Noah, Reyes-Gomez, Manuel, Heckerman, David, Jojic, Nebojsa

Journal:

Journal of Computational Biology

Year:

2008

Language:

english

File:

PDF, 283 KB

english, 2008

27

EMINIM: An Adaptive and Memory-Efficient Algorithm for Genotype Imputation

Kang, Hyun Min, Zaitlen, Noah A., Eskin, Eleazar

Journal:

Journal of Computational Biology

Year:

2010

Language:

english

File:

PDF, 3.51 MB

english, 2010

28

Response to Sul and Eskin

Price, Alkes L., Zaitlen, Noah A., Reich, David, Patterson, Nick

Journal:

Nature Reviews Genetics

Year:

2013

Language:

english

File:

PDF, 313 KB

english, 2013

29

Assessing allele-specific expression across multiple tissues from RNA-seq read data

Pirinen, Matti, Lappalainen, Tuuli, Zaitlen, Noah A., Dermitzakis, Emmanouil T., Donnelly, Peter, McCarthy, Mark I., Rivas, Manuel A.

Journal:

Year:

2015

Language:

english

File:

PDF, 164 KB

english, 2015

30

Variation in Predictive Ability of Common Genetic Variants by Established Strata

Aschard, Hugues, Zaitlen, Noah, Lindström, Sara, Kraft, Peter

Journal:

Year:

2015

Language:

english

File:

PDF, 460 KB

english, 2015

31

Mixed Model with Correction for Case-Control Ascertainment Increases Association Power

Hayeck, Tristan J., Zaitlen, Noah A., Loh, Po-Ru, Vilhjalmsson, Bjarni, Pollack, Samuela, Gusev, Alexander, Yang, Jian, Chen, Guo-Bo, Goddard, Michael E., Visscher, Peter M., Patterson, Nick, Price, A

Journal:

The American Journal of Human Genetics

Year:

2015

Language:

english

File:

PDF, 204 KB

english, 2015

32

Quantifying Missing Heritability at Known GWAS Loci

Gusev, Alexander, Bhatia, Gaurav, Zaitlen, Noah, Vilhjalmsson, Bjarni J., Diogo, Dorothée, Stahl, Eli A., Gregersen, Peter K., Worthington, Jane, Klareskog, Lars, Raychaudhuri, Soumya, Plenge, Robert

Journal:

Year:

2013

Language:

english

File:

PDF, 772 KB

english, 2013

33

Enhanced Statistical Tests for GWAS in Admixed Populations: Assessment using African Americans from CARe and a Breast Cancer Consortium

Pasaniuc, Bogdan, Zaitlen, Noah, Lettre, Guillaume, Chen, Gary K., Tandon, Arti, Kao, W. H. Linda, Ruczinski, Ingo, Fornage, Myriam, Siscovick, David S., Zhu, Xiaofeng, Larkin, Emma, Lange, Leslie A.,

Journal:

Year:

2011

Language:

english

File:

PDF, 652 KB

english, 2011

34

Informed Conditioning on Clinical Covariates Increases Power in Case-Control Association Studies

Zaitlen, Noah, Lindström, Sara, Pasaniuc, Bogdan, Cornelis, Marilyn, Genovese, Giulio, Pollack, Samuela, Barton, Anne, Bickeböller, Heike, Bowden, Donald W., Eyre, Steve, Freedman, Barry I., Friedman,

Journal:

Year:

2012

Language:

english

File:

PDF, 601 KB

english, 2012

35

Genetic and socioeconomic study of mate choice in Latinos reveals novel assortment patterns

Zou, James Y., Park, Danny S., Burchard, Esteban G., Torgerson, Dara G., Pino-Yanes, Maria, Song, Yun S., Sankararaman, Sriram, Halperin, Eran, Zaitlen, Noah

Journal:

Proceedings of the National Academy of Sciences

Year:

2015

Language:

english

File:

PDF, 937 KB

english, 2015

36

Multiple breast cancer risk variants are associated with differential transcript isoform expression in tumors

Caswell, Jennifer L., Camarda, Roman, Zhou, Alicia Y., Huntsman, Scott, Hu, Donglei, Brenner, Steven E., Zaitlen, Noah, Goga, Andrei, Ziv, Elad

Journal:

Human Molecular Genetics

Year:

2015

Language:

english

File:

PDF, 615 KB

english, 2015

37

Adapt-Mix: learning local genetic correlation structure improves summary statistics-based analyses

Park, Danny S., Brown, Brielin, Eng, Celeste, Huntsman, Scott, Hu, Donglei, Torgerson, Dara G., Burchard, Esteban G., Zaitlen, Noah

Journal:

Year:

2015

Language:

english

File:

PDF, 527 KB

english, 2015

38

Linkage Effects and Analysis of Finite Sample Errors in the HapMap

Zaitlen, Noah, Min Kang, Hyun, Eskin, Eleazar

Journal:

Year:

2009

Language:

english

File:

PDF, 333 KB

english, 2009

39

Sparse PCA corrects for cell type heterogeneity in epigenome-wide association studies

Rahmani, Elior, Zaitlen, Noah, Baran, Yael, Eng, Celeste, Hu, Donglei, Galanter, Joshua, Oh, Sam, Burchard, Esteban G, Eskin, Eleazar, Zou, James, Halperin, Eran

Journal:

Year:

2016

Language:

english

File:

PDF, 487 KB

english, 2016

40

Comment: A Human Genetics Perspective

Mefford, Joel A., Zaitlen, Noah A., Witte, John S.

Journal:

Journal of the American Statistical Association

Year:

2016

Language:

english

File:

PDF, 327 KB

english, 2016

41

PIGS: improved estimates of identity-by-descent probabilities by probabilistic IBD graph sampling

Park, Danny S, Baran, Yael, Hormozdiari, Farhad, Eng, Celeste, Torgerson, Dara G, Burchard, Esteban G, Zaitlen, Noah

Journal:

BMC Bioinformatics

Year:

2015

Language:

english

File:

PDF, 1005 KB

english, 2015

42

Transethnic Genetic-Correlation Estimates from Summary Statistics

Brown, Brielin C., Ye, Chun Jimmie, Price, Alkes L., Zaitlen, Noah

Journal:

The American Journal of Human Genetics

Year:

2016

Language:

english

File:

PDF, 728 KB

english, 2016

43

Selection and explosive growth alter genetic architecture and hamper the detection of causal rare variants

Uricchio, Lawrence H., Zaitlen, Noah A., Ye, Chun Jimmie, Witte, John S., Hernandez, Ryan D.

Journal:

Genome Research

Year:

2016

Language:

english

File:

PDF, 468 KB

english, 2016

44

DNA Methylation Profiling of Uniparental Disomy Subjects Provides a Map of Parental Epigenetic Bias in the Human Genome

Joshi, Ricky S., Garg, Paras, Zaitlen, Noah, Lappalainen, Tuuli, Watson, Corey T., Azam, Nidha, Ho, Daniel, Li, Xin, Antonarakis, Stylianos E., Brunner, Han G., Buiting, Karin, Cheung, Sau Wai, Coffee

Journal:

The American Journal of Human Genetics

Year:

2016

Language:

english

File:

PDF, 1.82 MB

english, 2016

45

Genetic Mechanisms Leading to Sex Differences Across Common Diseases and Anthropometric Traits

Traglia, Michela, Bseiso, Dina, Gusev, Alexander, Adviento, Brigid, Park, Daniel S., Mefford, Joel A., Zaitlen, Noah, Weiss, Lauren A.

Journal:

Year:

2017

File:

PDF, 40 KB

2017

46

Mixed Model Association with Family-Biased Case-Control Ascertainment

Hayeck, Tristan J., Loh, Po-Ru, Pollack, Samuela, Gusev, Alexander, Patterson, Nick, Zaitlen, Noah A., Price, Alkes L.

Journal:

The American Journal of Human Genetics

Year:

2017

Language:

english

File:

PDF, 175 KB

english, 2017

47

The Effects of Migration and Assortative Mating on Admixture Linkage Disequilibrium

Zaitlen, Noah, Huntsman, Scott, Hu, Donglei, Spear, Melissa, Eng, Celeste, Oh, Sam S., White, Marquitta J., Mak, Angel, Davis, Adam, Meade, Kelly, Brigino-Buenaventura, Emerita, LeNoir, Michael A., Bi

Journal:

Year:

2017

Language:

english

File:

PDF, 1.16 MB

english, 2017

48

Correcting for cell-type heterogeneity in DNA methylation: a comprehensive evaluation

Rahmani, Elior, Zaitlen, Noah, Baran, Yael, Eng, Celeste, Hu, Donglei, Galanter, Joshua, Oh, Sam, Burchard, Esteban G, Eskin, Eleazar, Zou, James, Halperin, Eran

Journal:

Year:

2017

Language:

english

File:

PDF, 101 KB

english, 2017

49

GLINT: a user-friendly toolset for the analysis of high-throughput DNA-methylation array data

Rahmani, Elior, Yedidim, Reut, Shenhav, Liat, Schweiger, Regev, Weissbrod, Omer, Zaitlen, Noah, Halperin, Eran

Journal:

Year:

2017

Language:

english

File:

PDF, 163 KB

english, 2017

50

Heritable natural variation of an anxiety-like behavior in larval zebrafish

Wagle, Mahendra, Nguyen, Juliana, Lee, Shinwoo, Zaitlen, Noah, Guo, Su

Journal:

Journal of Neurogenetics

Year:

2017

Language:

english

File:

PDF, 2.14 MB

english, 2017

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